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Coronary Heart Disease in the First 30 Years of the 21st Century: Challenges and Opportunities

Presented by George Beller, MD at American Heart Association Meeting Nov 14, 2000

Published in Circulation 2001:103:2428-2435    4 quotes    added 6/01/01

"Starting statins in the hospital after MI reduced 1-year mortality by 34%.  Early coronary revascularization reduced mortality by 36%.  The combination of starting statins in the hospital and coronary angioplasty reduced mortality (1-year) by a remarkable 64%."  based on 22,000 patients in Sweden.

"We can still do better to improve survival after acute MI.  More expansive and effective out-of-hospital defibrillation for potential sudden cardiac death victims and preventing delays to initial reperfusion therapy must be accomplished."

"According to the American Heart Association's statistical update for 2000, 59,700,000 Americans had cardiovascular disease.  Of these, 12,200,000 had CHD, 7,200,000 have had a MI, and 4,600,000 were alive with congestive heart failure.  Heart disease is now the most common diagnosis in hospitalized patients 65 years of age or older."

"Diabetes adversely affects cardiovascular outcomes.  Diabetics with no clinical evidence of CHD have the same risk for future cardiac death and nondiabetics with a prior infraction.  The absolute risk of CHD death at any concentration of cholesterol is 3 to 5 times higher in the presence of diabetes." article has 3 pages of details as to why this is so.