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Influence of Admission Body Temperature on Stroke Mortality added 10/05/00

in Stroke Feb 2000 pg 404 - 409

In results summary: " The odds ratio for in-hospital mortality in hypothermic versus normothermic {normal temperature} patients was 0.1."

Article starts with "It is well accepted that alterations in body temperature can profoundly affect the mortality from ischemic stroke in laboratory animal models, in which treatment with mild hypothermia (30 to 34 decrees Centegrade) has been shown to reduce the size of cerebral infarction."

This analysis was done on 509 stroke patients in New South Wales Australia who were either ischemic (86%) or hemorrhagic (14%).

Mild hypothermia, < 36.5 degrees, was measured in 42% of the patients.

While there was a difference during the first year, the 1 year survival in the group with hypothermia was not statistically different from that in those with normothermia.

months

0 3 6 9 12
Hypothermia 182 176 176 173 168
Normothermia 170 158 154 152 150

Note: there was no attempt in this study to cool the stroke patient.

A later study in the same journal actively cooled the patient.