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Abstracts of articles of Skyaid interest
              Most Journals were NOT available from Univ. of Wash. Medical Library          added 12/15/00

J Accid Emerg Med 2000 Nov;17(6):392-5     UW Med Lib does not subscribe to this  
A national census of ambulance response times to emergency calls in Ireland.  

 
Breen N, Woods J, Bury G, Murphy AW, Brazier H  
 Department of General Practice, University College Dublin, The Coombe Healthcare Centre, Ireland.  
BACKGROUND: Equity of access to appropriate pre-hospital emergency care is a core principle underlying an effective ambulance service. Care must be provided within a timeframe in which it is likely to be effective. A national census of response times to emergency and urgent calls in statutory ambulance services in Ireland was undertaken to assess current service provision. METHODS: A prospective census of response times to all emergency and urgent calls was carried out in the nine ambulance services in the country over a period of one week. The times for call receipt, activation, arrival at and departure from scene and arrival at hospital were analysed. Crew type, location of call and distance from ambulance base were detailed. The type of incident leading to the call was recorded but no further clinical information was gathered. Results-2426 emergency calls were received by the services during the week. Fourteen per cent took five minutes or longer to activate (range 5-33%). Thirty eight per cent of emergencies received a response within nine minutes (range 10-47%). Only 4.5% of emergency calls originating greater than five miles from an ambulance station were responded to within nine minutes (range 0-10%). Median patient care times for "on call" crews were three times longer than "on duty" crews. CONCLUSION: Without prioritised use of available resources, inappropriately delayed responses to critical incidents will continue. Recommendations are made to improve the effectiveness of emergency medical service utilisation.

 Ann Emerg Med 1993 Aug;22(8):1254-7  
Ambulance arrival to patient contact: the hidden component of prehospital response time intervals.  

 
Campbell JP, Gratton MC, Salomone JA 3d, Watson WA  
 Department of Emergency Medicine, School of Medicine, University of Missouri-Kansas City.  
 STUDY OBJECTIVE: To determine the time between ambulance arrival at the scene to paramedic arrival at the patient (arrival to patient contact) and the effect of barriers to paramedic movement on this time interval. DESIGN: A prospective, observational study. Time intervals were collected by independent third-party riders on emergency (Code 1 and Code 2) calls. Potential barriers to paramedic movement were recorded. SETTING: Public utility model urban emergency medical services system. TYPE OF PARTICIPANTS: Two hundred thirty-two emergency ambulance calls were observed, and data were analyzed from 216. INTERVENTIONS: None. RESULTS: The median arrival-to-patient contact interval for all calls was 1.33 minutes (interquartile range, 0.67 to 4.13 minutes). Barriers prolonged the arrival-to-patient contact interval (P < .001, Kolmogorov-Smirnov test). The median arrival-to-patient contact interval was 2.29 minutes (1.01 to 4.82 minutes) for 122 runs with barriers and 0.82 minutes (0.37 to 1.96 minutes) for 94 runs without barriers. CONCLUSION: The arrival-to-patient contact interval adds a variable and potentially lengthy amount of time to the total prehospital response time interval, and barriers impeding paramedic movement to the patient prolong this time interval. In 25% of all observed paramedic calls, the arrival-to-patient contact interval was more than four minutes. Measurement of the time from ambulance arrival on the scene to paramedic arrival at the patient is necessary to appropriately determine the relationship among total prehospital response time, paramedic interventions, and patient outcome.

Prehosp Emerg Care 2000 Oct-Dec;4(4):327-32          UW Med Lib does not subscribe to this
 
Delays in the EMS response to and the evacuation of patients in high-rise buildings in Singapore.  

 
Lateef F, Anantharaman V  
 Department of Emergency Medicine, Singapore General Hospital, Singapore. f_lateef@hotmail.com

 BACKGROUND: Singapore is a highly urbanized and cosmopolitan city situated at the crossroads of Southeast Asia. High-rise buildings and "vertical living" are common, and the city serves as a major business, financial, and industrial hub in the region. More than 80% of the population live in high-rise apartments. This poses unique problems and challenges for emergency ambulance services personnel in the access to and evacuation of patients. OBJECTIVE: To estimate the arrival-to-patient contact delay when accessing patients in high-rise buildings and evacuating them to the hospital, compared with accessing patients in ground-level premises. METHODS: This was a prospective study carried out from February 2 to March 1, 1998, for emergency calls from two of the busiest fire stations. The first 150 consecutive cases were enrolled into each of the two groups. Cases of road traffic accidents were excluded because these did not require the crew to get into a building. The times were clocked by one of the paramedics, using a stopwatch. A high-rise building was defined as one where the crew had to ascend at least one flight of stairs. A ground-level building did not involve any stair climbing. We set forth to determine whether the interval between the following was statistically significant when comparing high-rise vs ground-level premises: 1) time when the ambulance arrives at the scene (taken as the time when the driver turns the engine off) and time of arrival at the patient's side; 2) time of leaving the dwelling with the patient and time when the ambulance starts its journey to the hospital (taken as the time when the driver starts the engine). Data analysis was done with the use of SPSS, and the one-tailed unpaired Student's t-test was used for significance testing, with the alpha error rate set at 0.05. Results. One hundred fifty runs were analyzed for each group. The mean delay from arrival to patient contact was 2.49 +/- 0.98 minutes for the high-rise group compared with 1.02 +/- 1.41 minutes for the ground-level group (difference was statistically significant with 95% CI: 1.20, 1.74 minutes; p = 0.0106). The mean delays from the time of leaving the building with the patient to the time when the ambulance turned its engine on to start its journey to the hospital were 3.24 +/- 1.58 minutes and 1.27 +/- 0.71 minutes for the two groups, respectively (difference was statistically significant with 95% CI: 1.68, 2.04 minutes; p = 0.0098). CONCLUSION: There were significant delays present when accessing patients in high-rise buildings and evacuating them to the hospital. Modification to buildings and increasing public awareness and education have been suggested to help minimize these delays.

  Health Devices 2000 Sep;29(9):301-34                      UW Med Lib no longer subscribes to this  Defibrillator/monitor/pacemakers.  
 Defibrillator/monitors allow operators to assess and monitor a patient's ECG and, when necessary, deliver a defibrillating shock to the heart. When integral noninvasive pacing capability is added, the resulting device is referred to as a defibrillator/monitor/pacemaker. In this Update Evaluation, we present our findings for nine such units, including complete Product Profiles for two newly evaluated models and update information for seven other models evaluated in our May-June 1993 and February 1998 studies. We tested the two newly evaluated models using the same basic protocol as in our previous studies. However, we did add some new tests--and revise some old ones--to account for advances in the technology. These advancements include the increasing use of advisory modes and the increasing availability of expanded monitoring capabilities (which allow units to function, at least to some degree, like a physiologic monitor). As in our previous studies, we rated each model separately for three common defibrillation applications: (1) general crashcart use, (2) in-hospital transport use, and (3) prehospital use by emergency medical services (EMS) personnel. Because each application requires its own set of capabilities, it's not surprising that few models are appropriate for all applications. However, we did identify three models that perform well--earning a rating of either Acceptable or Preferred--in all three areas

  Minerva Anestesiol 2000 Jul-Aug;66(7-8):503-16                  UW Med Lib does not subscribe to this  
 
The chain of survival. A review in year 2000.  

 
Gullo A, Sallusti R, Trillo G  
 Department of Anesthesiology and Intensive Care, Trieste University School of Medicine.

 Worldwide about 1 in 1000 adults every year has a sudden cardiac arrest in out-of-hospital. That means 350,000-400,000 persons in the USA alone, 60,000 persons in Italy. Over 70% of times sudden cardiac arrest occurs at home, the remaining 30% in public settings. The chain of survival concept emphasizes four links associated with survival after sudden cardiac arrest corresponding each with a set of actions that have been done as soon as possible--the early access, the early CPR, the early defibrillation, the early ACLS; in order to develop strength in each link, separate specialized programs are needed, but all of the links must be well connected. The Utstein Style was developed by a task force who suggested a series of recommendations as a starting point for more effective exchange of information about out-of hospital cardiac arrest. The Utstein Style includes a glossary of terms, a template for reporting data from resuscitation studies on cardiac arrest, definitions for time points and time intervals related to an intervention in a resuscitation attempt, definitions of clinical items and outcomes that should be included in reports, and recommendations for the descriptions for how different EMS systems are organized.

Prehosp Emerg Care. 2000 Jul-Sep;4(3):270-2. No abstract available      UW Med Lib does not subscribe to this
Acute stroke: implications for prehospital care. National Association of EMS Physicians Standards and Clinical Practice Committee.

  Crit Care Nurs Clin North Am 1999 Jun;11(2):261-8   
 
Developing an emergency department team for treatment of stroke with recombinant tissue plasminogen activator.  

 
Gonzaga-Camfield R  
 Department of Neurology, Long Island Jewish Medical Center, New Hyde Park, New York, USA.

 The EMS, ED, neurology, radiology, nursing, laboratory, and pharmacy departments are integral parts of the stroke team system. These are the key departments responsible for the support of the stroke team, or nucleus, which emanates from the departments of neurology and emergency medicine in the author's medical center. In the same way that cardiac victims are treated for "heart attack," so stroke victims should be treated for "brain attack." The emphasis on public awareness to community outreach and senior citizens groups through the aid of the public affairs department of the institution, the American Heart Association, and the National Stroke Association (NSA) has been a tremendous lift in this, the decade of the brain. The Public Broadcasting System and other television channels have helped enormously in publicizing stroke signs and symptoms, new treatment of stroke, and concurrent risk factors. New clinical research for thrombolytics and neuro-protective agents are now in progress to determine the best treatment for the damaged brain. The emphasis is changing: Time is brain. We hope to change the expenditure attributable to rehabilitation and managed care after stroke to the more hopeful prospects of prevention, early treatment, and fast recovery. We can then see that our friends and family members, as victims of stroke, may proceed to independence rather than long-term care facilities or nursing homes. This will be possible only if hospitals and medical centers nationwide adequately gear themselves for the treatment of ischemic stroke through the creation of a core stroke team, finely-honed interdepartmental cooperation, and the development of an efficient ED team that is fully immersed in the ethics and protocol of "brain attack."  

Acad Emerg Med 1998 Jan;5(1):45-51         UW Med Lib does not subscribe to this     
Rapid response to stroke symptoms: the Delay in Accessing Stroke Healthcare (DASH) study.  

Rosamond WD, Gorton RA, Hinn AR, Hohenhaus SM, Morris DL  
 Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC. wayne_rosamond@unc.edu

 OBJECTIVE: To assess the determinants of prehospital delay for patients with presumed acute cerebral ischemia (ACI) in order to provide the background necessary to develop interventions to shorten such delays. METHODS: A prospective registry of patients presenting to the ED with signs and symptoms of stroke was established at a university hospital from July 1995 to March 1996. Trained nurses performed a structured ED interview, which assessed prehospital delay and potential confounders. RESULTS: The median delay (interquartile range) from symptom onset to ED arrival for all patients seeking care for stroke-like symptoms (n = 152) was 3.0 hours (1.5-7.8 hr). The median delay from symptom onset to ED arrival was less in cases where a witness first recognized that there was a serious problem than it was when the patient first identified the problem. A heightened sense of urgency by the patient about his or her symptoms, and use of 911/emergency medical services (EMS) transport were also associated with rapid arrival in the ED within 3 hours of symptom onset. After adjusting for all predictor variables in a multivariable logistic regression model, only recognition of symptoms by a witness and calling 911/EMS transport remained statistically significant. CONCLUSIONS: These data suggest that future efforts to intervene on prolonged prehospital delay for patients with ACI should include strategies for the community as a whole as well as persons at risk for stroke and should reinforce the use of 911 and EMS transport.

Stroke 2000 Nov;31(11):2591-6
Determinants of use of emergency medical services in a population with stroke symptoms : the second delay in accessing stroke healthcare (DASH II) study.  

 
Schroeder EB, Rosamond WD, Morris DL, Evenson KR, Hinn AR  
 Department of Epidemiology (E.B.S., W.D.R., K.R.E.), School of Public Health, and the Departments of Emergency Medicine (D.L.M.) and Neurology (A.H.), School of Medicine, University of North Carolina, Chapel Hill.

 Background and Purpose-With the advent of time-dependent thrombolytic therapy for ischemic stroke, it has become increasingly important for stroke patients to arrive at the hospital quickly. This study investigates the association between the use of emergency medical services (EMS) and delay time among individuals with stroke symptoms and examines the predictors of EMS use. METHODS:-The Second Delay in Accessing Stroke Healthcare Study (DASH II) was a prospective study of 617 individuals arriving at emergency departments in Denver, Colo, Chapel Hill, NC, and Greenville, SC, with stroke symptoms. RESULTS:-EMS use was associated with decreased prehospital and in-hospital delay. Those who used EMS had a median prehospital delay time of 2.85 hours compared with 4.03 hours for those who did not use EMS (P:=0.002). Older individuals were more likely to use EMS (odds ratio [OR] 1.21 for each 5-year increase, 95% CI 1.14 to 1.29), as were individuals who expressed a high sense of urgency about their symptoms (OR 1.69, 95% CI 1.09 to 2.62). Knowledge of stroke symptoms was not associated with increased EMS use (OR 0.63, 95% CI 0.40 to 0.98). Patients were more likely to use EMS if someone other than the patient first identified that there was a problem (OR 2.35, 95% CI 1.61 to 3.44). CONCLUSIONS:-Interventions aimed at increasing EMS use among stroke patients need to stress the urgency of stroke symptoms and the importance of calling 911 and need to be broad-based, encompassing not only those at high risk for stroke but also their friends and family.

   Prehosp Emerg Care 1999 Jul-Sep;3(3):201-6        UW Med Lib does not subscribe to this 
 
A nationwide prehospital stroke survey.  

 
Crocco TJ, Kothari RU, Sayre MR, Liu T  
 Department of Emergency Medicine, University of Cincinnati, Ohio 45267-0769, USA. todd.crocco@uc.edu

 OBJECTIVES: To identify deficiencies in stroke knowledge among prehospital providers. METHODS: A nationwide multiple-choice survey was sent to 689 paramedics (EMT-Ps) and 294 advanced EMTs (EMT-Is) from a random selection of the National Registry of Emergency Medical Technicians database. Of the 23 questions, five addressed demographic information, four quantity of training, five general knowledge, 6 and seven management, and two open-ended questions addressed the signs, symptoms, and risk factors of stroke. The EMT-P and EMT-I answers were compared using chi-square analysis or Fisher's exact test. RESULTS: Of the 355 (36%) respondents, 256 (72%) were EMT-Ps and 99 (28%) were EMT-Is. Virtually all the EMT-Ps (99%) and EMT-Is (98%) knew that a stroke injures the brain, but only 199 (78%) of the EMT-Ps and 47 (47%) of the EMT-Is correctly defined a transient ischemic attack (TIA) (p < 0.001). Slurred speech, weakness/ paralysis, and altered mental status were the three most commonly cited symptoms of stroke by both groups. The EMT-Ps were more likely to recognize that dextrose is potentially harmful to stroke patients [EMT-P = 216 (85%), EMT-I = 71 (72%), p = 0.005]; 169 (66%) of the EMT-Ps and 75 (76%) of the EMT-Is felt that elevated blood pressures should be lowered in the prehospital setting. Only 93 (36%) of the EMT-Ps and 22 (22%) of the EMT-Is knew that tissue plasminogen activator (tPA) must be given within three hours of symptom onset (p = 0.01). CONCLUSION: Most EMS providers are knowledgeable about the symptoms of stroke but are unaware of the therapeutic window for thrombolysis and the recommended avoidance of prehospital blood pressure reduction. In addition, further education is needed regarding TIAs

  J Am Acad Nurse Pract 1998 Dec;10(12):559-68; quiz 569-71
Acute ischemic stroke.
 
 
Hall P  
 Washington State University, USA.

 To optimize the recovery outcome of those with acute ischemic stroke, several steps need to be taken and strengthened by the public and medical personnel. These include immediate identification of stroke symptoms and appropriate actions, quick access to EMS, rapid EMS response, treatment and evacuation, early communication to the medical facility, rapid diagnosis and interventions, specialized treatment, evaluation of complications, precipitating and accompanying factors, and appropriate rehabilitation when applicable.

  Acad Emerg Med 1998 Apr;5(4):352-8        UW Med Lib does not subscribe to this   
Ensuring the chain of recovery for stroke in your community.
 
 
Pepe PE, Zachariah BS, Sayre MR, Floccare D  
 Allegheny University of the Health Sciences, Allegheny University Hospitals, Allegheny General, Pittsburgh, PA 15212-4772, USA. ppepe@aherf.edu

 Until recently, the prehospital and ED management of nonhemorrhagic stroke was largely supportive care. Studies have now demonstrated the potential of certain therapeutic interventions to reverse the debilitating consequences of such strokes. The clinical benefit for such interventions and the risk of significant therapeutic complications are highly time-dependent. To optimize the chances of a better outcome for the patient with stroke, each community must establish and continue to refine a chain of recovery for stroke patients. The chain of recovery is a metaphor that describes a series of sequential actions that must take place in a timely fashion to optimize the chances of recovery from stroke. Each of these sequential actions forms an individual link in the chain, and each link must be intact. The links include: identification of the onset of stroke symptoms by the patient or bystanders; dispatch life support services, which preferably include enhanced 9-1-1 and medically supervised and trained dispatchers who can rapidly deploy the closest responders and transport units; emergency medical services (EMS) personnel who can rapidly assess and transport the stroke patient to the closest appropriate center capable of providing advanced stroke diagnostics and interventions; en route notification of the receiving facility so that appropriate personnel can be readied for rapid diagnosis and intervention; and receiving facilities capable of providing rapid diagnosis and advanced treatment of stroke, including the availability of specialists who can evaluate underlying etiologies as well as plan future therapies and rehabilitation. To ensure that the chain of recovery is in place, aggressive public education campaigns should be implemented to increase the probability that stroke symptoms and signs will be recognized as soon as possible by patients and bystanders. In addition, because most of the current training programs for EMS dispatchers and EMS personnel are lacking with regard to stroke, it is recommended that such personnel and their EMS system managers be updated on current management and treatment strategies for stroke.

Stroke 2000 Sep;31(9):2251-6  
Feasibility and safety of inducing modest hypothermia in awake patients with acute stroke through surface cooling: A case-control study: the Copenhagen Stroke Study.
 
 
Kammersgaard LP, Rasmussen BH, Jorgensen HS, Reith J, Weber U, Olsen TS  
 Department of Neurology, Bispebjerg, Copenhagen, Denmark. kammersgaard@dadlnet.dk

 BACKGROUND AND PURPOSE: Hypothermia reduces neuronal damage in animal stroke models. Whether hypothermia is neuroprotective in patients with acute stroke remains to be clarified. In this case-control study, we evaluated the feasibility and safety of inducing modest hypothermia by a surface cooling method in awake patients with acute stroke. METHODS: We prospectively included 17 patients (cases) with stroke admitted within 12 hours from stoke onset (mean 3.25 hours). They were given hypothermic treatment for 6 hours by the "forced air" method, a surface cooling method that uses a cooling blanket with a flow of cool air (10 degrees C). Pethidine was given to treat compensatory shivering. Cases were compared with 56 patients (controls) from the Copenhagen Stroke Study matched for age, gender, initial stroke severity, body temperature on admission, and time from stroke onset to admission. Blood cytology, biochemistry, ECGs, and body temperature were monitored during hypothermic treatment. Multiple regression analyses on outcome were performed to examine the safety of hypothermic therapy. RESULTS: Body temperature decreased from t(0)=36.8 degrees C to t(6)=35.5 degrees C (P:<0.001), and hypothermia was present until 4 hours after therapy (t(0)=36.8 degrees C versus t(10)=36.5 degrees C; P:=0.01). Mortality at 6 months after stroke was 12% in cases versus 23% in controls (P:=0. 50). Final neurological impairment (Scandinavian Stroke Scale score at 6 months) was mean 42.4 points in cases versus 47.9 in controls (P:=0.21). Hypothermic therapy was not a predictor of poor outcome in the multivariate analyses. CONCLUSIONS: Modest hypothermia can be achieved in awake patients with acute stroke by surface cooling with the "forced air" method, in combination with pethidine to treat shivering. It was not associated with a poor outcome. We suggest a large, randomized clinical trial to test the possible beneficial effect of induced modest hypothermia in unselected patients with stroke.

  Cochrane Database Syst Rev 2000;(2):CD001247
 
Cooling therapy for acute stroke.  

 
Correia M, Silva M, Veloso M  
 Neurology Department, Hospital Geral de Santo Antonio, Largo Prof Abel Salazar, Porto, Portugal, 4050. nedcv@mail.telepac.pt

 BACKGROUND: Recent studies in acute stroke patients have shown an association between body temperature and prognosis. OBJECTIVES: Our objective was to assess the effects of cooling when applied to patients with acute ischaemic stroke or primary intracerebral haemorrhage. SEARCH STRATEGY: We searched the Cochrane Stroke Group's trial register (last searched in March 1999), plus MEDLINE searched up to November 1998 and EMBASE searched from January 1980 to November 1998. We contacted investigators, pharmaceutical companies and manufacturers of cooling equipment in this field. SELECTION CRITERIA: All completed randomised controlled trials or controlled clinical trials, published or unpublished, where cooling therapy (therapy given by physical devices or antipyretic drugs primarily to lower body temperature independently of basal temperature at the beginning of treatment) was applied up to two weeks of an acute ischaemic stroke or primary intracerebral haemorrhage. DATA COLLECTION AND ANALYSIS: Two reviewers independently searched for relevant trials. MAIN RESULTS: No randomised trials or controlled trials were identified; one placebo-controlled trial of metamizol is currently underway. REVIEWER'S CONCLUSIONS: There is currently no evidence from randomised trials to support the routine use of physical or chemical cooling therapy in acute stroke. Since experimental studies showed a neuroprotective effect of hypothermia in cerebral ischaemia, and hypothermia appears to improve the outcome in patients with severe closed head injury, trials with cooling therapy in acute stroke are warranted.

Minera Anestesiol July 2000   UW Med Lib does not subscribe to this 

EMS  UW Med Lib does not subscribe to this 

J Card. Failure  Sept 96  UW Med Lib does not subscribe to this 

J Cardiovascualr Elect  Feb 2000  UW Med Lib does not subscribe to this 

J of Telemedicine   UW Med Lib does not subscribe to this 

Phys Med Rehabil Clin N Am - - - - - - - UofW?

Status of functional outcomes for stroke survivors. 1999 Nov;10(4):957-66. Review.

Stroke. Neurologic and functional recovery the Copenhagen Stroke Study. 1999 Nov;10(4):887-906. Review.

Air Med J (no U of W) - - - - - - - 

Pilot study for predicting appropriate use of air medical helicopters. Part 1: Interfacility transports.  2000 Apr-Jun;19(2):59-65. No abstract

Justifying cardiac transports. 2000 Apr-Jun;19(2):37. No abstract

J Insur Med. (no U of W) Morbidity and mortality associated with stroke 1996;28(1):13-22. Review. No abstract available

J Hum Hypertens (no  U of W)  Fifty years of Framingham Study contributions to understanding hypertension. 2000 Feb;14(2):83-90. Review

Cardiovasc Drugs Ther.  no U of W  1999 Apr;13(2):95-104. Review. Cardiovascular disease in developing countries: myths, realities, and opportunities.

Cerebrovasc Dis.  No U of W 1999 Nov-Dec;9(6):320-2.  Stroke during sleep: epidemiological and clinical features.

Eur J Emerg Med. No U of W 1999 Mar;6(1):61-9. Review. Stroke--a medical emergency.

Indian J Med Res. No U of W 1997 Oct;106:325-32. Review. Strokes in the elderly: prevalence, risk factors & the strategies for prevention.

Manag Care Q.   No U of W 2000 Winter;8(1):38-43. "Low-tech" personal emergency response systems reduce costs and improve outcomes.

Prehosp Emerg Care. No U of W 1999 Jul-Sep;3(3):201-6.  A nationwide prehospital stroke survey.